An odor reported at Charlotte Douglas International Airport on Friday sent a number of crew members to the hospital with unspecified injuries, American Airlines said in a statement.
Before passengers boarded Flight 2055 on Friday, the odor was reported, the airline said.
Crew members received medical attention on site, the airline said, adding that some were taken to the hospital, where they were treated and later released.
NBC affiliate WCNC Charlotte reported that seven people were taken to the hospital for treatment. Six people had minor injuries and one person had serious symptoms, the outlet reported.
It was not immediately clear what the odor was or where it came from. The nature of the injuries was also not clear, but WCNC reported they were a result of inhaling something.
The involved airplane was taken out of service and will be inspected, American Airlines said.